A cross-sectional analysis identified co-authorship networks and scientific collaboration on reporting guidelines for health research.

OBJECTIVES: To investigate scientific collaboration and citation metrics of reporting guidelines for health research. STUDY DESIGN AND SETTING: A cross-sectional analysis of published articles of reporting guidelines for health research. A search of the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) Network Library (from inception to January 21, 2021) was supplemented by searching websites of guideline developers. For each article, metadata (e.g., authors, institutions, countries, citations) were extracted from the Web of Science and Scopus (up to October 25, 2021). Descriptive analyses were conducted. Network analyses of collaborations were presented. RESULTS: We included 662 articles published in 332 journals. The BMJ (n = 50 articles; 8%), Annals of Internal Medicine (n = 29; 4%), and Journal of Clinical Epidemiology (n = 24; 4%) published the largest number of articles. Four thousand seven hundred twenty two authors, 1,647 institutions, and 83 countries were involved. The global productivity was led by the United States (n = 456 articles), the United Kingdom (n = 414), and Canada (n = 306). We found eight clusters of authors (e.g., one major group with 337 members) and three clusters of institutions (e.g., one major group with 256 members). The most prolific authors were affiliated with the Ottawa Hospital Research Institute (Canada), the University of Ottawa (Canada), the University of Oxford (the United Kingdom), and Stanford University (the United States). CONCLUSION: Our analysis identified key actors producing reporting guidelines, most intense collaborations, and 'citation classics' in the field. These results could potentially be used to strengthen collaborations for developing and disseminating reporting guidelines for health research.

Financed research from Government Delegation grants for the National Plan on Drugs: Research assessment and scientific impact. / Repercusión científica de las ayudas de la Delegación del Gobierno para el Plan Nacional sobre Drogas: Publicaciones derivadas e impacto científico.

Addictive disorders are a serious health problem to which large amounts of research resources are devoted. This study aims to analyze the evolution and scientific impact of the publications derived from the funding of research projects by the Spanish National Plan on Drugs (PNSD). The list of grants awarded was provided by the PNSD. Derived publications were obtained by asking the principal investigators of the grants and searching in the Web of Science and Scopus. Bibliometric indicators and evolutive trends of scientific production per project were calculated. On average, the PNSD conferred 15 annual grants to research projects, with an annual amount close to one million euros (€944,200.64) and an average amount per grant of just over €60,000, being higher in basic research and in alcohol. 71,9% of the grants had derived publications and almost half of them produced between one and three publications, with basic research being the most prolific. The international journal in which most articles were published was Psychopharmacology (50) and among Spanish journals, Adicciones stood out (28). A high level of co-authorship and international collaboration was identified. Most of the PNSD-funded projects produced research articles, many of them in journals belonging to the first and second quartiles of the Journal Citation Reports. The results of this study have revealed the scientific impact of the PNSD research projects funding and may contribute to determining future funding priorities.

Los trastornos adictivos son un grave problema de salud al que se destinan gran cantidad de recursos de investigación. El propósito de este trabajo es analizar la evolución e impacto científico de las publicaciones derivadas de las ayudas a proyectos de investigación financiados por el Plan Nacional Sobre Drogas (PNSD). La relación de ayudas concedidas fue proporcionada por el PNSD. Las publicaciones derivadas se obtuvieron preguntando a los investigadores principales de las ayudas y buscando en Web of Science y Scopus. Se calcularon indicadores bibliométricos y tendencias evolutivas de la producción científica por proyecto. Por término medio, el PNSD concedió 15 ayudas anuales a proyectos de investigación, con un importe anual cercano al millón de euros (944.200,64€) y un importe medio por ayuda de algo más de 60.000€, siendo mayor en la investigación básica y en alcohol. El 71,9% de las ayudas tuvieron publicaciones derivadas y casi la mitad produjeron entre una y tres publicaciones, siendo la investigación básica la más prolífica. La revista extranjera en la que más artículos se publicaron fue Psychopharmacology (50) y entre las españolas destacó Adicciones (28). Se identificó un alto índice de coautoría y de colaboración internacional. La mayoría de los proyectos financiados por el PNSD produjeron artículos de investigación y muchos de ellos en revistas del primer y segundo cuartil del Journal Citation Reports. Los resultados de este estudio han permitido conocer la repercusión científica de las ayudas a proyectos de investigación del PNSD y puede contribuir a determinar futuras prioridades de financiación.

Repercusión científica de las ayudas de la Delegación del Gobierno para el Plan Nacional sobre Drogas: Publicaciones derivadas e impacto científico / Financed research from Government Delegation grants for the National Plan on Drugs: Research assessment and scientific impact

Los trastornos adictivos son un grave problema de salud al que se destinan gran cantidad de recursos de investigación. El propósito de este trabajo es analizar la evolución e impacto científico de las publicaciones derivadas de las ayudas a proyectos de investigación financiados por el Plan Nacional Sobre Drogas (PNSD). La relación de ayudas concedidas fue proporcionada por el PNSD. Las publicaciones derivadas se obtuvieron preguntando a los investigadores principales de las ayudas y buscando en Web of Science y Scopus. Se calcularon indicadores bibliométricos y tendencias evolutivas de la producción científica por proyecto. Por término medio, el PNSD concedió 15 ayudas anuales a proyectos de investigación, con un importe anual cercano al millón de euros (944.200,64€) y un importe medio por ayuda de algo más de 60.000€, siendo mayor en la investigación básica y en alcohol. El 71,9% de las ayudas tuvieron publicaciones derivadas y casi la mitad produjeron entre una y tres publicaciones, siendo la investigación básica la más prolífica. La revista extranjera en la que más artículos se publicaron fue Psychopharmacology (50) y entre las españolas destacó Adicciones (28). Se identificó un alto índice de coautoría y de colaboración internacional. La mayoría de los proyectos financiados por el PNSD produjeron artículos de investigación y muchos de ellos en revistas del primer y segundo cuartil del Journal Citation Reports. Los resultados de este estudio han permitido conocer la repercusión científica de las ayudas a proyectos de investigación del PNSD y puede contribuir a determinar futuras prioridades de financiación. (AU)

Addictive disorders are a serious health problem to which large amounts of research resources are devoted. This study aims to analyze the evolution and scientific impact of the publications derived from the funding of research projects by the Spanish National Plan on Drugs (PNSD). The list of grants awarded was provided by the PNSD. Derived publications were obtained by asking the principal investigators of the grants and searching in the Web of Science and Scopus. Bibliometric indicators and evolutive trends of scientific production per project were calculated. On average, the PNSD conferred 15 annual grants to research projects, with an annual amount close to one million euros (€944,200.64) and an average amount per grant of just over €60,000, being higher in basic research and in alcohol. 71,9% of the grants had derived publications and almost half of them produced between one and three publications, with basic research being the most prolific. The international journal in which most articles were published was Psychopharmacology (50) and among Spanish journals, Adicciones stood out (28). A high level of co-authorship and international collaboration was identified. Most of the PNSD-funded projects produced research articles, many of them in journals belonging to the first and second quartiles of the Journal Citation Reports. The results of this study have revealed the scientific impact of the PNSD research projects funding and may contribute to determining future funding priorities. (AU)

Global Trends in Scientific Research on Pediatric Obesity.

(1) Introduction: The aim of this study was to analyze scientific production, collaboration among countries, and research topics focusing on pediatric obesity. (2) Methods: The papers that were included in the study were retrieved from the Web of Science Core Collection from Clarivate Analytics. A bibliometric analysis of several focuses, including journals of publication, subject categories, most frequent author keywords, and journal impact factors, was conducted. Social network analysis was used to recognize collaboration groups between countries and the co-occurrences of author keywords. (3) Results: A total of 12,171 research articles were published in 2036 journals classified under a variety of subject areas, with pediatrics (27.7%), nutrition and dietetics (18.5%), and public environmental and occupational health (18.4%) accounting for the most frequent study areas, and Pediatric Obesity (309), the International Journal of Obesity (299), and BMC Public Health being the most productive journals. The main challenges identified for pediatric obesity include general topics such as physical activity, nutrition, diet, and prevention as well as other more specific challenges such as metabolic syndrome, insulin resistance, eating behavior, and cardiovascular diseases. (4) Conclusions: We observed a growth rate in the number of published articles of 59.8%, which serves as evidence of the importance of the topic. The number of funded papers also doubled from 2010 to 2019. There has been significant global collaboration on the topic, with countries across five continents being involved. The results of the thematic analysis reveal the importance of exercise and nutrition-related topics along with specialized health terms and terms related to public health.

The impact of Ibero-American science on global bioethical thinking.

The bioethics research conducted in Ibero-American countries has been very much restricted to its own realm. The aim of this study was to perform a bibliometric evaluation of bioethics papers by authors affiliated with Ibero-American institutions, and to determine how their work influences global bioethics literature. We performed a literature search in the Web of Science Core Collection (WoS CC) and Scopus. We identified a total of 5,975 documents, of which 84.3% were articles, 11.6% reviews and 4.1% book chapters. The median number of citations per paper was higher in English-language journals. Only 10 articles published between 2010 and 2019 in peer-reviewed bioethics journals and produced exclusively by authors from Ibero-American institutions garnered more than 15 citations. Our study suggests that if researchers from Ibero-American institutions want to influence global bioethical thinking, they must make the required leap in quality to be able to publish in high-quality bioethics and mainstream journals.

Global scientific production regarding behavioral addictions: An analysis of the literature from 1995 to 2019.

AIMS: The increase in scientific interest in so-called behavioral addictions has been growing in recent years. For this reason, the aim of our study is to use bibliometric techniques to identify where and with what intensity these behaviors are being studied. METHODS: In October 2020, we conducted a search in the Web of Science Core Collection using a search equation designed to retrieve the articles that combine the general keywords of addiction with specific terms of the 7 groups of behavioral addictions analyzed (gambling; gaming; information and communication related disorders; and the so-called somatic addictions related to sex, shopping, food and sports). Articles published from 1995 to 2019 were included. RESULTS: We found 9199 distinct articles. Gambling was the most studied addiction, but Information and Technology Communication-related disorders (ITC) had the highest growth rate over the span of five five-year periods, followed by gaming and food addiction. In general, there was a growth rate of 130.46% in the research on behavioral addiction issues. By geographical region, the United States was the most productive country regarding all addictions, but Oceania had the highest proportion of publications per million population. There was a clear interest among Asian countries in studying problems related to ITC and gaming problems. CONCLUSIONS: The importance of the seven behavioral addictions analyzed according to their growth rate in scientific research fields over the last 25 years was confirmed in our study. In addition, the differences in interest by geographical region show us that it is important to delve deeper into cultural particularities to better understand this phenomenon.

[COVID-19 and Smoking: A Systematic Review and Meta-Analysis of the Evidence]. / COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia.

OBJECTIVE: The aim of this study was to determine if tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcome, and if smoking, current and past, is associated with a greater possibility of developing COVID-19. MATERIAL AND METHODS: A systematic review (SR) and meta-analysis (MA) of previously published works were performed. The search strategy included all known descriptors for Covid-19 and tobacco and was conducted in different databases. Appropriate statistical models were used to address the effect size in meta-analysis, namely random effects and fixed effects model. RESULTS: Thirty-four articles were identified in the SR of which 19 were included in the MA. Being a smoker or former smoker was shown to be a risk factor for worse progression of Covid-19 infection (OR 1.96, 95% CI, 1.36 - 2.83) and a greater probability of presenting a more critical condition (OR 1.79 95% CI, 1.19 - 2.70). As limitations of the MA, we found that most of the studies analyzed were observational with limited publication bias. Two studies that disagreed with the rest were included, although after withdrawing them from the MA, smoking was maintained as a risk factor for worse progress. CONCLUSION: Current and past smoking produces a more serious clinical form of Covid-19 and more frequently leads to intensive care admission, intubation, and death.

Mapping the scientific research on radiology departments: Global trends in publication, collaboration and trending topics.

PURPOSE: To characterize the global research trend in radiology departments based on bibliometric indicators. MATERIAL AND METHOD: As a source of information, Science Citation Index Expanded and Journal Citation Reports from Web of Science Core Collection (WoSCC) were used. Annual trends, journals of publication, subject categories of journals, collaboration indexes between authors and institutions, network of cowords and most cited papers were identified and analysed. The period of study was 2009-2018. RESULTS: 283,587 downloaded papers were analysed. The number of articles was increasing, as well as the percentage of funded works. Papers were published in 7314 different journals, being the most productive Plos One (5077), followed by American Journal of Roentgenology (4602) and European Radiology (3644). Most productive subject categories of journals were Radiology, Nuclear Medicine & Medical Imaging (86,568 papers), Clinical Neurology (29,722) and Surgery (23,564). International collaboration has increased more than 5 points, from 15.2% in 2009 to 20.7% in 2018. CONCLUSIONS: Most cited articles were published in high impact journals outside the scope of diagnostic imaging. Most influential topics included technical innovations within imaging modalities. MRI replaced conventional radiography and CT as the imaging technique of choice in imaging research.

Worldwide production on sleep apnea from 2009-2018. Analysis of the ability to secure funding and international collaboration networks.

BACKGROUND: Obstructive sleep apnea (OSA) is an emerging health problem, but information on scientific production in this subject area is scarce. We aim to evaluate the scientific production on OSA from 2009 to 2018 to illustrate its worldwide distribution, topic areas, and ability to secure funding, as well as to describe international collaboration networks in this field. METHODS: Articles published between 2009 and 2018 were extracted from the Science Citation Index Expanded via Web of Science (WoS) using the search term "obstructive sleep apn*". Publication year, number and country of authors, journal, subject category, key words, funding source and number of citations received were recorded. We also conducted network analyses for key words and international collaboration. RESULTS: 12,666 articles on OSA were located, which had increased from 895 documents in 2009 to 1592 in 2018. The progressive growth in scientific production on OSA had outpaced the growth rate of total WoS production since 2012.50% of the articles declared some type of funding, with a citation index higher than manuscripts that were not funded. The manuscripts were distributed in journals from 135 subject categories of the WoS, and keyword distribution showed a dispersed pattern with a high number of nodes. The international collaboration rate was 18.2%, and the country network showed the United States as the hegemonic node. CONCLUSION: World production on OSA has grown at a higher rate than global production and shows notable thematic dispersion as well as a high ability to secure funding, which increases its impact.

The sharing of research data facing the COVID-19 pandemic.

During the previous Ebola and Zika outbreaks, researchers shared their data, allowing many published epidemiological studies to be produced only from open research data, to speed up investigations and control of these infections. This study aims to evaluate the dissemination of the COVID-19 research data underlying scientific publications. Analysis of COVID-19 publications from December 1, 2019, to April 30, 2020, was conducted through the PubMed Central repository to evaluate the research data available through its publication as supplementary material or deposited in repositories. The PubMed Central search generated 5,905 records, of which 804 papers included complementary research data, especially as supplementary material (77.4%). The most productive journals were The New England Journal of Medicine, The Lancet and The Lancet Infectious Diseases, the most frequent keyword was pneumonia, and the most used repositories were GitHub and GenBank. An expected growth in the number of published articles following the course of the pandemics is confirmed in this work, while the underlying research data are only 13.6%. It can be deduced that data sharing is not a common practice, even in health emergencies, such as the present one. High-impact generalist journals have accounted for a large share of global publishing. The topics most often covered are related to epidemiological and public health concepts, genetics, virology and respiratory diseases, such as pneumonia. However, it is essential to interpret these data with caution following the evolution of publications and their funding in the coming months.

WITHDRAWN: Reply to "Smoker, Former Smoker and COVID-19: Nicotine Does Not Protect Against SARS-CoV-2"

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal

Respuesta a "Fumador, exfumador y COVID-19" / Reply to "Smoker, Former Smoker and COVID-19"

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Trends in funding research and international collaboration on greenhouse gas emissions: a bibliometric approach.

The Web of Science Core Collection platform was used to withdraw the papers included in this study. The studied period comprised from inception till 2018. Trends in research, journals of publication, subject areas of research, keywords most frequently used, countries of publication, international collaboration, and trends of funding research were also analyzed. A total of 3902 articles were published, most of them (52.5%) during the five-year period 2014-2018. The area with the highest number of papers was environmental sciences (41%), followed by energy fuels (16.6%) and engineering environmental (15.7%). "Nitrous oxide emissions" was the most frequent word, followed by "Carbon dioxide emissions" and "Methane emissions". Other words that stood out were "Life cycle assessment", "Climate change" and "Environmental impacts". The United States was the country with the highest productivity (27.9%), followed by China (12.8%) and the United Kingdom (9.6%). There was a concentration of research in recent years, as more than 80% of the papers were published in the last 10 years. The journals that published the largest number of publications were devoted mainly to environmental studies (sciences and engineering), sustainable and green science and technology, energy and fuels, economics, and agriculture. Half of the works were published in Europe and the other half between North America and Asia. Two thirds of the works (67%) were financed compared to a third that were not financed. The percentage of funded works has been increasing over the last decade, which is seen as an indication of the importance of GHGE.

The most 100 cited papers in addiction research on cannabis, heroin, cocaine and psychostimulants. A bibliometric cross-sectional analysis.

The number of citations a peer-reviewed article receives is often used as a measure of its importance and scientific impact. This paper identifies, describes and categorizes the highly cited papers in addiction research on cannabis, heroin, cocaine and psychostimulants. Highly cited papers were identified in the Web of Science Core Collection database. Several bibliometric indicators were calculated. Social network analysis was applied to draw groups of authors and institutions with the greatest number of collaborations and co-words. The number of citations for the top 100 cited articles ranged from 649 to 4,672. The articles were published in 40 journals. The subject category Substance Abuse included 10 papers. The United States was the most productive country (79 papers), followed by the United Kingdom (9). The main funding institutions were the National Institutes of Health in the United States. The network of collaboration between authors distributes the 352 researchers into 53 groups. The three most cited works address the neural basis of drug craving as an incentive-sensitization theory of addiction, the clinical and research uses of the Addiction Severity Index, and the neurocircuitry of addiction. Scientific literature on addictions is widely dispersed both in multidisciplinary and specific journals of neurology, psychiatry and addictions, with relatively few publications providing most of the citations. An ongoing challenge for this field is the concentration of highly cited papers coming from a select number of countries, with the United States being the research hub of the world, with the highest volume of publications and total citations.

Trend in Spanish cardiology research and global comparative analysis of major topics.

INTRODUCTION AND OBJECTIVES: We used bibliometric techniques to analyze the participation of Spanish institutions in research on major cardiovascular topics during the last 4 decades. METHODS: Bibliometric indicators of production, collaboration and impact were obtained from the Science Citation Index Expanded (SCIE) database. Search strategies were used in major topics and institutional collaboration networks were identified, represented using the Kamada-Kawai algorithm. RESULTS: Global cardiovascular publications doubled from 2000 to 2018. In 2018, those by Spanish authors represented 2.33%, with a participation of between 7% and 1.84%, depending on the topics analyzed. The offset with respect to global production was between 0 and 7 years. Annual growth rates were higher in more recent topics. Revista Española de Cardiología published the largest number of articles from Spanish institutions. The journals generating the highest number of citations in the chosen topics were the Journal of the American College of Cardiology, Europace, and the European Heart Journal. Analysis of collaboration revealed a close interrelation between Spanish and foreign institutions, as well as groups with high production publishing independently. CONCLUSIONS: The analysis disaggregated by subject showed the sustained growth of Spanish cardiovascular scientific production and more rapid growth in recently appearing topics. Collaboration networks showed a high degree of interrelation between Spanish and foreign institutions, including hospitals, universities, research institutes, and scientific societies.

COVID-19 y tabaquismo: revisión sistemática y metaanálisis de la evidencia / COVID-19 and Smoking: A Systematic Review and Meta-Analysis of the Evidence

OBJETIVO: El objetivo del estudio ha sido responder a las siguientes preguntas: ¿se asocia el consumo de tabaco en pacientes con COVID-19 con una progresión negativa y desenlace adverso de la enfermedad? y, ¿se asocia el consumo de tabaco, actual y pasado a una mayor posibilidad de desarrollar COVID-19? MATERIAL Y MÉTODOS: Se realizó una revisión sistemática (RS) y metaanálisis (MA) de trabajos publicados previamente. La estrategia de búsqueda incluyó todos los descriptores conocidos sobre COVID-19 y tabaco, y se realizó en diferentes bases de datos. Se utilizaron modelos estadísticos adecuados para abordar el tamaño del efecto en un MA: modelo de efectos aleatorios y de efectos fijos. RESULTADOS: Fueron identificados 34 artículos en la RS de los cuales fueron incluidos 19 en el MA. Ser fumador o exfumador se mostró como un factor de riesgo para una peor progresión de la infección por COVID-19 (OR 1,96, IC del 95%, 1,36-2,83) y una mayor probabilidad de presentar una condición más crítica de la infección (OR 1,79, IC del 95%, 1,19-2,70). Como limitaciones del MA encontramos que la mayoría de los estudios analizados eran observacionales con un sesgo de publicación limitado y con 2 estudios discrepantes con el resto, aunque tras retirarlos del MA se mantenía el tabaco como un factor de riesgo de peor evolución. CONCLUSIÓN: El tabaquismo actual y pasado produce una forma clínica más grave de la COVID-19 y lleva con mayor frecuencia a estos pacientes a ingresar en Cuidados Intensivos, sean intubados y mueran

OBJECTIVE: The aim of this study was to determine if tobacco use in patients with Covid-19 is associated with a negative disease course and adverse outcome, and if smoking, current and past, is associated with a greater possibility of developing COVID-19. MATERIAL AND METHODS: A systematic review (SR) and meta-analysis (MA) of previously published works were performed. The search strategy included all known descriptors for Covid-19 and tobacco and was conducted in different databases. Appropriate statistical models were used to address the effect size in meta-analysis, namely random effects and fixed effects model. RESULTS: Thirty-four articles were identified in the SR of which 19 were included in the MA. Being a smoker or former smoker was shown to be a risk factor for worse progression of Covid-19 infection (OR 1.96, 95% CI, 1.36 - 2.83) and a greater probability of presenting a more critical condition (OR 1.79 95% CI, 1.19 - 2.70). As limitations of the MA, we found that most of the studies analyzed were observational with limited publication bias. Two studies that disagreed with the rest were included, although after withdrawing them from the MA, smoking was maintained as a risk factor for worse progress. CONCLUSION: Current and past smoking produces a more serious clinical form of Covid-19 and more frequently leads to intensive care admission, intubation, and death

Gender inequalities on editorial boards of indexed pediatrics journals.

BACKGROUND: The presence of women in decision-making positions, such as on editorial committees of biomedical journals, is not the same as that of men. This paper analyzes the gender composition of editorial committees (EBMs) and editors-in-chief (ECs) positions of pediatric journals. METHODS: The gender of EBMs and ECs of 125 journals classified in the pediatrics area of the Journal Citation Report (JCR) was analyzed. The following indicators were calculated: gender distribution of ECs and EBMs by journal, publisher, subject speciality, country, quartile of the journal in JCR and country of affiliation of the members. RESULTS: The total number of EBMs was 4242. The distribution by sex of the ECs was 19.44% women and 80.56% men, while that of the EBMs were 33.05% women and 66.95% men. Twenty journals exhibited a greater representation of women than of men, and in four there was parity. Journals with greater participation of women specialized in nursing and physical therapy and were related to nutrition (lactation and breastfeeding). CONCLUSIONS: Only one-fifth of ECs and one-third of EBMs are females. Women's participation is higher in journals related to nursing, physical and occupational therapy, and nutrition. The United States has the highest number of EBMs, followed by the European Union. IMPACT: Only one-fifth of Editors-in-chief in pediatrics journals are female. Only one-third of Editorial Board Members in pediatrics journals are female. Women's participation is higher in editorials committees in pediatrics journals related to nursing, physical and occupational therapy, and nutrition. Medical and pediatric associations and societies must work together to eliminate the disparities that exist between women and men. Achieving gender equity and empowering all women is one of the World Health Organization's Sustainable Development Goals.

Worldwide Scientific Research on Nanotechnology: A Bibliometric Analysis of Tendencies, Funding, and Challenges.

The main objective of this investigation was to analyze the scientific production in global research on nanotechnology, integrating scientific production, funding of studies, collaborations between countries, and the most cited publications. The source for obtaining the research papers for our analysis was the Science Citation Index Expanded from the Web of Science. A total of 3546 documents were extracted during the period of 1997-2018. Food science & technology, chemistry (applied and analytical), spectroscopy, and agriculture appeared as the main areas where the articles were published. Most prolific and cited journals were Analytical Methods, Journal of Agricultural and Food Chemistry, and Food Chemistry. The co-word analysis showed the relationships between "nanoparticles", which is the central word, and "silver nanoparticles", "delivery systems", and "zinc-nanoparticles". The most productive countries were China (1089 papers), the United States (523), Iran (427), and India (359). The main cited topics deal with the biomedical applications of nanoparticles, its synthesis from plants, and its applications in food science. The results highlight an important collaboration between institutions and countries. The availability of funding for research in nanotechnology was remarkable compared to other fields. The multidisciplinarity of the nanotechnology field is one of the main features as well as one of the central findings.